Statistics of Primera División Uruguaya in season 1988.
It was contested by 13 teams, and Danubio won the championship.
| Pos | Club | P | W | D | L | GF | GA | Pts |
| 1 | Danubio | 24 | 18 | 4 | 2 | 52 | 18 | 40 |
| 2 | Peñarol | 24 | 13 | 5 | 6 | 51 | 30 | 31 |
| 3 | Defensor | 24 | 12 | 7 | 5 | 33 | 17 | 31 |
| 4 | Huracán Buceo | 24 | 11 | 6 | 7 | 25 | 25 | 28 |
| 5 | Liverpool | 24 | 10 | 5 | 9 | 20 | 21 | 25 |
| 6 | Montevideo Wanderers | 24 | 6 | 12 | 6 | 25 | 26 | 24 |
| 7 | Nacional | 24 | 8 | 6 | 10 | 26 | 32 | 22 |
| 8 | Cerro | 24 | 9 | 3 | 12 | 21 | 29 | 21 |
| 9 | Central Español | 24 | 7 | 7 | 10 | 19 | 27 | 21 |
| 10 | River Plate | 24 | 5 | 10 | 9 | 26 | 27 | 20 |
| 11 | Bella Vista | 24 | 5 | 8 | 11 | 20 | 33 | 18 |
| 12 | Miramar Misiones | 24 | 4 | 10 | 10 | 24 | 38 | 18 |
| 13 | Progreso | 24 | 4 | 5 | 15 | 20 | 39 | 13 |
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